Catuama herbal product
Catuama is an herbal product very popular in Brazil. Catuama (a mixture of Trichilia catigua, Paullinia cupana, Ptychopetalum olacoides, and Zinziber officinalis).
The herbal drug Catuama reverts and prevents ventricular fibrillation in the
isolated rabbit heart.
J Electrocardiol. 2007 Sep 21;
Pontieri V, Neto AS, de França Camargo AF, Koike MK, Velasco IT.
Emergency Medicine Research Laboratory, Medical School of University of São
Paulo, São Paulo, Brazil.
Catuama was tested on the reversion and prevention of ventricular fibrillation
(VF) in the isolated rabbit heart. Catuama was perfused in the
isolated perfused rabbit heart. Its effects on intraventricular conduction,
heart rate, and monophasic action potential (MAP) duration were evaluated, and
sustained ventricular fibrillation was induced. The effects on reversion and reinduction of arrhythmia
were observed, and new measures were taken in the hearts that reverted. Catuama and T catigua reverted
ventricular fibrillation in all hearts, prevented reinduction, and
prolonged intraventricular conduction. Catuama prolonged MAP phase 2. On the
other hand, P cupana reverted ventricular fibrillation in 3 of 5 hearts, but depressed automatism,
prolonged MAP phase 3, and did not prevent reinduction. Catuama
reverted and prevented ventricular fibrillation in this model. T catigua extract
is probably the main agent responsible for the beneficial actions observed.
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